DEPENDENCE OF RETINAL MORPHOFUNCTIONAL PARAMETERS ON SUBMACULAR HEMORRHAGE AREA
https://doi.org/10.25881/20728255_2025_20_4_S1_139
Abstract
Objective: to analyze the morphofunctional parameters of the retina in submacular fracture of various areas on the background of age-related macular degeneration. A prospective study was conducted, which included 109 eyes (98 patients) divided into 3 groups of hemorrhages of different sizes.
Results: Statistical analysis revealed significant differences between groups of patients with different areas of QMS in the ICOS between all pairs of groups: when comparing groups 1 and 2 (U = 1228, p<0.001), groups 2 and 3 (U = 1254, p<0.001), and 1Groups 2 and 3 (U = 1254, p<0.001). Correlation analysis using Spearman’s r-criterion revealed a strong inverse relationship between the area of the QMS and the indicators of the ICOS (rS = -0.81), as well as a strong positive relationship between the values of the CTS and the area of the QMS (rS = 0.85).
Conclusion: The data obtained demonstrate that an increase in the area of submacular hemorrhage leads to a progressive deterioration in the functional state of the retina.
About the Authors
E. D. BosovRussian Federation
Moscow
M. M. Shishkin
Russian Federation
Moscow
A. A. Dolganova
Russian Federation
Moscow
R. R. Fayzrakhmanov
Russian Federation
Moscow
I. Kh. Khusanov
Russian Federation
Moscow
V. B. Smirnova-Sotmari
Russian Federation
Moscow
References
1. Патоморфология субмакулярного кровоизлияния (обзор) / Р. Р. Файзрахманов, М. М. Шишкин, Э. Д. Босов [и др.] // Саратовский научно-медицинский журнал. – 2021. – Т. 17, № 1. – С. 28-32. Pathomorphology of Submacular Hemorrhage (Review) / Faizrakhmanov R. R., Shishkin M.M., Bosov E. D.
2. Дифференцированный подход к лечению пациентов с субретинальным кровоизлиянием на фоне возрастной макулодистрофии / Д. В. Петрачков [и др.] // Современные технологии в офтальмологии. – 2023. – Т. 47, № 1. – С. 123–127. A differentiated approach to the treatment of patients with subretinal hemorrhage caused by age-related macular degeneration / D. V. Petrachkov
3. Новые данные о патогенетических механизмах развития возрастной макулярной дегенерации / А. Ж. Фурсова [и др.] // Вестник офтальмологии. – 2022. – Т. 138, № 2. – С. 120–130/ New data on the pathogenetic mechanisms of age-related macular degeneration / A. Zh. Fursova
4. Management of extensive subfoveal haemorrhage secondary to neovascular age-related macular degeneration / S. Sacu [et al.] // Eye. – 2009. – № 23. – P. 1404–1410.
5. Оценка динамики морфологических параметров сетчатки у пациентов с субфовеальным кровоизлиянием на фоне ВМД / Р. Р. Файзрахманов, Э. Д. Босов, А. В. Суханова // Современные технологии в офтальмологии. – 2021. – № 3(38). – С. 179-184. Evaluation of the dynamics of retinal morphological parameters in patients with subfoveal hemorrhage against the background of AMD / R. R. Faizrakhmanov, E. D. Bosov, A. V. Sukhanova
Review
For citations:
Bosov E.D., Shishkin M.M., Dolganova A.A., Fayzrakhmanov R.R., Khusanov I.Kh., Smirnova-Sotmari V.B. DEPENDENCE OF RETINAL MORPHOFUNCTIONAL PARAMETERS ON SUBMACULAR HEMORRHAGE AREA. Bulletin of Pirogov National Medical & Surgical Center. 2025;20(4):139-144. (In Russ.) https://doi.org/10.25881/20728255_2025_20_4_S1_139