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PERSONALIZED APPROACH TO THE PROGNOSIS AND PREVENTION OF INTRA-ABDOMINAL ADHESIONS AFTER APPENDECTOMY

https://doi.org/10.25881/20728255_2025_20_3_64

Abstract

Rationale: The incidence of acute appendicitis is 708 cases per 10000 population. Postoperative complications after open appendectomy were 2.35 to 10%, after laparoscopic appendectomy from 4.9% to 6.2%. Abdominal interventions are accompanied by the development of intra-abdominal adhesions in 14.0% of patients, after repeated interventions – in 90.0-96.0% of the operated patients.
Purpose: To determine the efficacy of anti-adhesion therapy after appendectomy.
Materials and methods: 60 patients with acute appendicitis who underwent open appendectomy. Men – 19 (31.7%), women – 41 (68.3%). The control group consisted of 30 (50%) patients who did not undergo prevention of intra-abdominal adhesions in the postoperative period, and another 30 (50%) patients who received anti-adhesion therapy (main group). To calculate the risk of intra-abdominal adhesions after ppendectomy, we have developed an “Assistant program for determining the effectiveness of the treatment method and preventing the development of postoperative intra-abdominal adhesions”.
Results: By the method of rating testing, it was established that the highest risk of developing postoperative intra-abdominal adhesions is present in patients who do not receive a set of anti-adhesion measures. Anti-adhesion therapy in patients after appendectomy reduces the risk of intra-abdominal adhesions by 1.97 times, improves the quality of life of operated patients.
Conclusion: When performing abdominal operations, it is necessary to form groups of patients with a tendency to the formation of intra-abdominal adhesions, for whom anti-adhesion therapy is indicated in order to reduce the risk of developing an adhesive process in the abdominal cavity.

About the Authors

P. M. Lavreshin
Stavropol State Medical University
Russian Federation

Stavropol



V. K. Gobejishvili
Stavropol State Medical University
Russian Federation

Stavropol



V. V. Gobejishvili
I.M. Sechenov First Moscow State Medical University
Russian Federation

Moscow 



S. S. Korablina
Stavropol State Medical University
Russian Federation

Stavropol



M. K. Chotchaev
Stavropol State Medical University
Russian Federation

Stavropol



P. I. Chumakov
Stavropol State Medical University
Russian Federation

Stavropol



M. A. Uzdenov
Stavropol State Medical University
Russian Federation

Stavropol



References

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3. Zenicheva AV. Modern approaches to the diagnosis and treatment of acute appendicitis and its complications. In the collection: Molodezhnaya nauka i sovremennost’. Proceedings of the 88th International Scientific Conference of Students and Young Scientists. 2023: 349-351. (In Russ.)

4. Revishvili ASh, Olovyanny VE, Kalinin DV, еt al. Lethality in acute appendicitis. Khirurgiya. Zhurnal im. N.I. Pirogova. 2022; 10: 5-14. (In Russ.) doi: 10.17116/hirurgia20221015.

5. Rybakov KD, Sednev GS, Morozov AM, et. al. Prevention of the formation of adhesions in the abdominal cavity (a review of literature).Vestnik novyh medicinskih tekhnologij. 2022; 29(1): 22-28. (In Russ.) doi: 10.24412/1609-2163-2022-1-22-28.

6. Sukovatykh BS, Blinkov YYu, Valuiskaya NM, et al. Results of treatment of patients with ventral hernias and peritoneal adhesions after widespread peritonitis. Vestnik Nacional’nogo medikohirurgicheskogo centraim. N.I. Pirogova. 2022; 17(1): 45-48. (In Russ.) doi: 10.25881/20728255.

7. Certificate №2024680628/30.08.24. Uzdenov MA, Lavreshin PM, Gobezhishvili VK, et al. Certificate of State Registration of a Computer Program. Program-assistant for determining the effectiveness of a treatment method in prevention of postoperative intra-abdominal adhesions. (In Russ.)

8. Certificate №20246656-63/03.07.24. Uzdenov MA, Lavreshin PM, Gobezhishvili VK, et al. Program-assistant for determining the risk of postoperative intra-abdominal adhesions. (In Russ.)


Review

For citations:


Lavreshin P.M., Gobejishvili V.K., Gobejishvili V.V., Korablina S.S., Chotchaev M.K., Chumakov P.I., Uzdenov M.A. PERSONALIZED APPROACH TO THE PROGNOSIS AND PREVENTION OF INTRA-ABDOMINAL ADHESIONS AFTER APPENDECTOMY. Bulletin of Pirogov National Medical & Surgical Center. 2025;20(3):64-68. (In Russ.) https://doi.org/10.25881/20728255_2025_20_3_64

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ISSN 2072-8255 (Print)
ISSN 2782-3628 (Online)