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ANALYSIS OF EARLY CHANGES IN OPTICAL COHERENCE TOMOGRAPHY AND OCULAR MANIFESTATIONS OF VOGT-KOYANAGI-HARADA DISEASE (CLINICAL CASES)

https://doi.org/10.25881/20728255_2024_19_4_S1_96

Abstract

The difficulty of diagnosing Vogt-Koyanagi-Harada syndrome is due to the fact that in the prodromal stage, the inflammatory process develops in the vascular membrane without ocular manifestations, clinically, flu-like syndrome, meningism come out in the first place, mistakenly leading the patient to a doctor of another specialty.

Objective: To analyze optical coherence tomography (OCT) data and clinical manifestations for early diagnosis and timely treatment of Vogt-Koyanagi-Harada syndrome.

Methods: Data from two clinical cases are presented: patient T. with timely pathogenetic pulse therapy and patient B. with alternative treatment due to his refusal of the proposed therapy. Results: Against the background of treatment, both patients have an increase in visual acuity, but patient B. has a less favorable prognosis according to OCT data due to the lack of adequate therapy.

Conclusion: OCT of the macular region makes it possible to make the correct diagnosis at an early date, which prevents the transition of the uveitic stage of Vogt-Koyanagi-Harada disease into a chronic one.

About the Authors

R. M. Zakirov
State Autonomous Healthcare Institution «RCOH of the Ministry of Health of the Republic of Tatarstan named after Professor E.V. Adamyuk»; KSMA – Branch Campus of the FSBEIFPE RMACPE MOH Russia
Russian Federation

Kazan



I. H. Sabirova
State Autonomous Healthcare Institution «RCOH of the Ministry of Health of the Republic of Tatarstan named after Professor E.V. Adamyuk»
Russian Federation

Kazan



E. A. Zhidenko
State Autonomous Healthcare Institution «RCOH of the Ministry of Health of the Republic of Tatarstan named after Professor E.V. Adamyuk»
Russian Federation

Kazan



L. N. Sabirova
KSMA – Branch Campus of the FSBEIFPE RMACPE MOH Russia
Russian Federation

Kazan



References

1. Кански Дж.Дж., Милевски С.А., Дамато Б.Э., Тэннер В. Заболевания глазного дна. – Пер. с англ. – 2-е изд. ⁄ Под общ. ред. чл.-корр. РАМН, проф. С.Э. Аветисова. – М.: МЕДпресс-информ, 2009. – 424 с., ил

2. Fedotov V. P. Rasstroistva pigmentatsii kozhi (diskhromii)//DVKS. 2014. (In Russ.)

3. Katargina L. A., Denisova E. V., Starikova A. V., Gvozdyuk N. A. Clinical findings and treatment results in the Vogt-Koyanagi-Harada syndrome associated uveitis in children. Oftal’mologicheskie vedomosti. 2012; 5 (1): 36-44. (In Russ.)

4. Сенченко Н. Я., Щуко А. Г., Малышев В. В. Увеиты: руководство. М.: ГЕОТАР-Медиа; 2010.

5. Кацнельсон Л.А., Танковский В.Э. Увеиты (клиника, лечение).– М., 1998. – 203 с.

6. Bodmer W. //HLA 1997 Eds P.Terasaki, D.Gjertson. – 1998. – P. 1–7.

7. Boutimzine N., Laghmari A., Ouazzani I., Ibrahimy W., Mohcine Z. // J. Fr. Ophtalmol. – 1998. – Dec; 21 (10). – P. 746–754

8. Desarnaulds–A.B., Borruat–F.X., Herbort–C.P., Spertini–F. //Klin.–Monatsbl.–Augenheilkd. – 1996. – May. – 208 (5). – P. 301–302.

9. Mambetkulova G. K., Ishberdina L. Sh., Mal’khanov V. B. Immunologicheskie i immunogeneticheskie osobennosti uveitov pri sindrome Fogta-Koyanagi-Kharada. Russkii meditsinskii zhurnal. (In Russ.)

10. Rao N. A., Sukavatcharin S., Tsai J. H. Vogt-Koyanagi-Harada disease diagnostic criteria. Int. Ophthalmol. 2007; 27 (2-3): 195-9.8.2024).


Review

For citations:


Zakirov R.M., Sabirova I.H., Zhidenko E.A., Sabirova L.N. ANALYSIS OF EARLY CHANGES IN OPTICAL COHERENCE TOMOGRAPHY AND OCULAR MANIFESTATIONS OF VOGT-KOYANAGI-HARADA DISEASE (CLINICAL CASES). Bulletin of Pirogov National Medical & Surgical Center. 2024;19(4):96-99. (In Russ.) https://doi.org/10.25881/20728255_2024_19_4_S1_96

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ISSN 2072-8255 (Print)
ISSN 2782-3628 (Online)