pirogovestnikВестник Национального медико-хирургического центра им. Н.И. ПироговаBulletin of Pirogov National Medical & Surgical Center2072-82552782-3628Национальный медико-хирургический Центр им. Н.И. Пирогова10.25881/20728255_2025_20_1_127pirogovestnik-277Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWSЛАБОРАТОРНЫЕ ПОКАЗАТЕЛИ КОАГУЛЯЦИИ И ВОСПАЛЕНИЯ У ПАЦИЕНТОВ С КОРОНАВИРУСНОЙ ИНФЕКЦИЕЙLABORATORY INDICES OF COAGULATION AND INFLAMMATION IN PATIENTS WITH CORONAVIRUS INFECTIONАгаповА. Б.AgapovA. B.

Рязань

Ryazan

agapchik2008@yandex.ruКалининР. Е.KalininR. E.

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Ryazan

СучковИ. А.SuchkovI. A.

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Ryazan

МжаванадзеН. Д.MzhavanadzeN. D.

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Ryazan

ПоваровВ. О.PovarovV. O.

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Ryazan

НикифоровА. А.NikiforovA. A.

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Ryazan

СнегурС. В.SnegurS. V.

Рязань

Ryazan

ФГБОУ ВО «Рязанский государственный медицинский университет им. академика И.П. Павлова»; ГБУ РО «Областная клиническая больница»РоссияRyazan State Medical University named after Academician I.P. Pavlov of the Ministry of Health of the Russian Federation; Regional Clinical HospitalRussian FederationФГБОУ ВО «Рязанский государственный медицинский университет им. академика И.П. Павлова»РоссияRyazan State Medical University named after Academician I.P. Pavlov of the Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО «Рязанский государственный медицинский университет им. академика И.П. Павлова»; ГБУ РО «Городская клиническая больница скорой медицинской помощи»РоссияRyazan State Medical University named after Academician I.P. Pavlov of the Ministry of Health of the Russian Federation; City Clinical Hospital of Emergency Medical CareRussian FederationГБУ РО «Областная клиническая больница»РоссияRegional Clinical HospitalRussian Federation202509032025201127133Copyright © Агапов А.Б., Калинин Р.Е., Сучков И.А., Мжаванадзе Н.Д., Поваров В.О., Никифоров А.А., Снегур С.В., 20252025Агапов А.Б., Калинин Р.Е., Сучков И.А., Мжаванадзе Н.Д., Поваров В.О., Никифоров А.А., Снегур С.В.Agapov A.B., Kalinin R.E., Suchkov I.A., Mzhavanadze N.D., Povarov V.O., Nikiforov A.A., Snegur S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://submit.pirogov-vestnik.ru/jour/article/view/277

Пандемия коронавирусной инфекции показала мировому медицинскому сообществу то, что для эффективной терапии острого респираторного заболевания потребуется приложить многочисленные усилия. Ученым и клиницистам удалось разработать алгоритмы диагностики и лечения, выявлять пациентов с высоким риском тромботических осложнений и летального исхода. Для этого потребовалось изучить патогенез заболевания, в основе которого находится два состояния: коагулопатия и воспаление. Поэтому во время пандемии проводились лабораторные исследования показателей воспаления и свертываемости крови для поиска маркеров тромботических осложнений и маркеров, которые сигнализируют об ухудшении состояния. Расширение границ знаний в лабораторных исследованиях позволят применять более совершенное комплексное лечение, и снизит потенциальные осложнения коронавирусной инфекции.

The coronavirus pandemic has shown the global medical community that effective treatment of acute respiratory disease requires a lot of effort. Scientists and clinicians have managed to develop diagnostic and treatment algorithms, identify patients with a high risk of thrombotic complications and death. This required studying the pathogenesis of the disease, which is based on two conditions: coagulopathy and inflammation. Therefore, during the pandemic, laboratory studies of inflammation and blood clotting parameters were conducted to search for markers of thrombotic complications and markers that signal a deterioration in the condition. Expanding the boundaries of knowledge in laboratory research will allow for more advanced complex treatment and reduce potential complications of coronavirus infection.

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The authors declare that there are no conflicts of interest present.