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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pirogovestnik</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник Национального медико-хирургического центра им. Н.И. Пирогова</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Pirogov National Medical &amp; Surgical Center</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8255</issn><issn pub-type="epub">2782-3628</issn><publisher><publisher-name>Национальный медико-хирургический Центр им. Н.И. Пирогова</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25881/20728255_2024_19_3_153</article-id><article-id custom-type="elpub" pub-id-type="custom">pirogovestnik-169</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>ИНДИВИДУАЛЬНЫЙ ПОДХОД К ДИАГНОСТИКЕ УВЕИТА ТУБЕРКУЛЕЗНОЙ ЭТИОЛОГИИ: ОТ ТЕОРИИ К ПРАКТИКЕ</article-title><trans-title-group xml:lang="en"><trans-title>AN INDIVIDUAL APPROACH TO THE DIAGNOSIS OF UVEITIS OF TUBERCULOUS ETIOLOGY: FROM THEORY TO PRACTICE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гамзаев</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Gamzaev</surname><given-names>M. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Булдаков</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Buldakov</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">van.buldakov@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлова</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlova</surname><given-names>M. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романова</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanova</surname><given-names>D. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клиника №2 ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Moscow Research and Clinical Center for Tuberculosis Control</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАУ НМИЦ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федоров</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.N. Fedorov NMRC «MNTK «Eye microsurgery»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>25</day><month>10</month><year>2024</year></pub-date><volume>19</volume><issue>3</issue><fpage>153</fpage><lpage>155</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гамзаев М.Г., Булдаков И.А., Козлова М.И., Романова Д.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Гамзаев М.Г., Булдаков И.А., Козлова М.И., Романова Д.А.</copyright-holder><copyright-holder xml:lang="en">Gamzaev M.G., Buldakov I.A., Kozlova M.A., Romanova D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://submit.pirogov-vestnik.ru/jour/article/view/169">https://submit.pirogov-vestnik.ru/jour/article/view/169</self-uri><abstract><p>Внутриглазной туберкулез – великий мистификатор различных форм увеита, и его надо ставить в первый ряд в дифференциальной диагностике любого типа внутриглазного воспаления, а также четко дифференцировать его от других этиологий поражения хориоидеи, что представляет определенные сложности ввиду разнообразия, мозаичности, зачастую нетипичности клиники туберкулезного процесса. В статье представлено клиническое наблюдение увеита туберкулезного генеза, у больной Д. 61 года, который хорошо купировался неспецифической противовоспалительной терапией и антибактериальными препаратами. При проведении и оценки результатов дополнительных исследований, таких как компьютерная томография органов грудной клетки и высокоспецифичного TSPOT.TB теста было заподозрено наличие латентной туберкулезной инфекции у пациентки. В результате была поставлена проба с аллергеном туберкулезным рекомбинантным (АТР), по результатам которой авторы получили выраженную очаговую реакцию со стороны глаза. Таким образом, впервые в мировом научном сообществе представлена клиническая картина выраженной реакции глаза на пробу с АТР, так как на данный момент среди доступных источников отечественной и зарубежной литературы нет сведений, описывающих такую же реакцию на пробу с АТР, как в представленном клиническом примере. Автора отмечают, что неординарность течения туберкулеза зрительного анализатора обязывает врача правильно собирать анамнез, выбирать актуальные методы диагностики, верно оценивать их результаты и проводить оценку эффективности противотуберкулезной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Intraocular tuberculosis is a great mystifier of various forms of uveitis, and it should be put in the first row in the differential diagnosis of any type of intraocular inflammation, as well as clearly differentiate it from other etiologies of choroidal lesions, which presents certain difficulties due to the diversity, mosaic, and often atypical clinic of the tuberculosis process. The article presents a clinical observation of tuberculous uveitis in a 61-year-old patient D., which was well stopped by nonspecific anti-inflammatory therapy and antibacterial drugs. When conducting and evaluating the results of additional studies, such as computed tomography of the chest and a highly specific TSPOT.TB test, the patient was suspected to have a latent tuberculosis infection in the patient. As a result, a test with recombinant tuberculosis allergen (ATR) was performed, as a result of which the authors received a pronounced focal reaction from the eye. Thus, for the first time in the world scientific community, a clinical picture of a pronounced reaction of the eye to an ATR test is presented, since at the moment there is no information among the available sources of domestic and foreign literature that describes the same reaction to an ATR test as in the presented clinical example. The authors note that the eccentricity of the course of tuberculosis of the visual analyzer obliges the doctor to correctly collect an anamnesis, choose current diagnostic methods, correctly evaluate their results and evaluate the effectiveness of anti-tuberculosis therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>туберкулез глаза</kwd><kwd>проба с АТР</kwd><kwd>увеит</kwd><kwd>противотуберкулезная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ocular tuberculosis</kwd><kwd>ATP test</kwd><kwd>uveitis</kwd><kwd>anti-tuberculosis therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Global Tuberculosis Report. 2020. WHO.</mixed-citation><mixed-citation xml:lang="en">Global Tuberculosis Report. 2020. WHO.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Сюнякова Д.А. 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