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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pirogovestnik</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник Национального медико-хирургического центра им. Н.И. Пирогова</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin of Pirogov National Medical &amp; Surgical Center</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8255</issn><issn pub-type="epub">2782-3628</issn><publisher><publisher-name>Национальный медико-хирургический Центр им. Н.И. Пирогова</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25881/20728255_2024_19_3_150</article-id><article-id custom-type="elpub" pub-id-type="custom">pirogovestnik-168</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>ВАРИАНТЫ ХИРУРГИЧЕСКОЙ ТАКТИКИ И СТРУКТУРНЫЕ ИЗМЕНЕНИЯ В СТЕНКЕ ПИЩЕВОДА ПРИ СИНДРОМЕ БУРХАВЕ</article-title><trans-title-group xml:lang="en"><trans-title>VARIANTS OF SURGICAL TACTICS AND STRUCTURAL CHANGES IN THE ESOPHAGEAL WALL IN THE BURHAAVE SYNDROME</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демальдинов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Demaldinov</surname><given-names>D. A.</given-names></name></name-alternatives><email xlink:type="simple">demdanir@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мустафин</surname><given-names>Р. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Mustafin</surname><given-names>R. D.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куртусунов</surname><given-names>Б. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurtusunov</surname><given-names>B. T.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рожкова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhkova</surname><given-names>S. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Астраханский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ АО «Патологоанатомическое Бюро»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pathoanatomical bureau</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>25</day><month>10</month><year>2024</year></pub-date><volume>19</volume><issue>3</issue><fpage>150</fpage><lpage>152</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Демальдинов Д.А., Мустафин Р.Д., Куртусунов Б.Т., Рожкова С.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Демальдинов Д.А., Мустафин Р.Д., Куртусунов Б.Т., Рожкова С.В.</copyright-holder><copyright-holder xml:lang="en">Demaldinov D.A., Mustafin R.D., Kurtusunov B.T., Rozhkova S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://submit.pirogov-vestnik.ru/jour/article/view/168">https://submit.pirogov-vestnik.ru/jour/article/view/168</self-uri><abstract><p>Представляются два клинических наблюдения с использованием различных вариантов хирургической тактики при синдроме Бурхаве (спонтанном разрыве пищевода). Проведена оценка статуса пациентов, характера вмешательств, результатов гистологических исследований и исходов заболевания. В обоих наблюдениях поводом к госпитализации в торакальное отделение явился спонтанный разрыв пищевода, осложненный медиастинитом и эмпиемой плевры.Первому пациенту, 70 лет, было проведено консервативное лечение. В связи с возникшим на 7-е сутки аррозивным кровотечением в экстренном порядке выполнена тораколапаротомия, ушивание дефекта пищевода. В послеоперационном периоде произошло прогрессивное ухудшение состояния, связанное с несостоятельностью швов пищевода и острым инфарктом миокарда, закончившееся летальным исходом.Второму пациенту, 59 лет, была выполнена экстирпация пищевода с наложением гастро- и эзофагостомы. Достигнуто клиническое выздоровление с последующей реконструктивной операцией.</p></abstract><trans-abstract xml:lang="en"><p>Two clinical cases of surgical tactics options for Burhaаve syndrome (spontaneous perforation of the esophagus) are presented. The assessment of the status of patients, the nature of interventions, the results of histological examination and the outcomes of the disease was carried out.In both cases, the reason for hospitalization in the thoracic department was a spontaneous rupture of the esophagus, complicated by mediastinitis and pleural empyema.The first patient, 59 years old, underwent esophageal extirpation with the imposition of gastro- and esophagostomy. Сlinical recovery has been achieved with the reconstructive surgery was performed. The second patient, 69 years old, underwent conservative treatment. On the 7th day, there was an arrosive bleeding. A thoracolaparotomy and suturing of the esophageal defect were urgently performed. In the postoperative period, there was a progressive deterioration with the death for the esophageal sutures leak and coronary syndrome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>разрыв пищевода</kwd><kwd>синдром Бурхаве</kwd><kwd>экстирпация пищевода</kwd><kwd>гистологическое исследование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Boerhaave syndrome</kwd><kwd>case reports</kwd><kwd>esophageal perforation</kwd><kwd>esophagectomy</kwd><kwd>histological examination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Haba Y, Yano S, Akizuki H, et al. Boerhaave syndrome due to excessive alcohol consumption: two case reports. Int J Emerg Med. 2020; 13(1): 56. doi: 10.1186/s12245-020-00318-5.</mixed-citation><mixed-citation xml:lang="en">Haba Y, Yano S, Akizuki H, et al. Boerhaave syndrome due to excessive alcohol consumption: two case reports. 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